Is it safe to delete Messages and Mail data?
Protected Not by removing it in Finder or a cleaner.
Your message history and attachments. Manage it from Messages or Mail instead.
Where it is
~/Library/Messages~/Library/Mail
What “Protected” means
Another app or a sync service manages it. Removing it breaks that app or deletes it on every device. ClearMac won't move it to the Trash, and tells you where to manage it instead.
How ClearMac handles it
ClearMac shows how much space it uses and explains it, but won't move it to the Trash.
This page is generated from the same rule ClearMac uses on your Mac (messages-mail.data), so the app and this page always say the same thing.