Is it safe to delete iPhone & iPad software updates?
Rebuilds automatically Yes.
iOS and iPadOS updates downloaded for devices you sync with this Mac. Downloaded again if a device needs them.
Where it is
~/Library/iTunes/iPhone Software Updates
What “Rebuilds automatically” means
The app or tool that made it recreates it by itself the next time it's needed. Removing it only costs a little time. ClearMac pre-selects these items.
How ClearMac handles it
ClearMac pre-selects it in a cleanup and moves it to the Trash, so you can put it back until you empty the Trash.
This page is generated from the same rule ClearMac uses on your Mac (ios.software-updates), so the app and this page always say the same thing.